Ashutosh Chilkoti

Image of Ashutosh Chilkoti

Theo Pilkington Professor of Biomedical Engineering in the Edmund T. Pratt, Jr. School of Engineering

Ashutosh Chilkoti is a professor with Duke's Department of Biomedical Engineering, and Director of the Center for Biologically Inspired Materials and Materials Systems (CBIMMS).

My research in biomolecular engineering and biointerface science focuses on the development of new molecular tools and technology's that borrow from molecular biology, protein engineering, polymer chemistry and surface science that we then exploit for the development of applications that span the range from bioseparations, plasmonic biosensors, low-cost clinical diagnostics, and drug delivery.

Appointments and Affiliations
  • Theo Pilkington Professor of Biomedical Engineering in the Edmund T. Pratt, Jr. School of Engineering
  • Professor of Biomedical Engineering
  • Professor in the Department of Mechanical Engineering and Materials Science
  • Professor in the Department of Chemistry
  • Member of the Duke Cancer Institute
Contact Information:
Education:

  • Ph.D. University of Washington, 1991

Research Interests:

Chilkoti's research focuses on biomolecular materials and biointerface science and emphasizes the development of applications that span the range from bioseparations, biosensors, patterned biomaterials, and targeted drug delivery.

Specialties:

Polymer and Protein Engineering
Drug Delivery
Biological Materials
Sensing and Sensor Systems
Diagnostics
Biophotonics
Plasmonics
Cancer diagnostics and therapy

Awards, Honors, and Distinctions:

  • Pritzker Distinguished Lecture Award, Biomedical Engineering Society, 2013
  • Clemson Award for Contributions to the Literature, Society for Biomaterials, 2011
  • Humboldt Senior Researcher Award, Alexander Von Humboldt Foundation, 2010
  • Stansell Family Distinguished Research Award, Duke University, Pratt School of Engineering, 2008
  • Distinguished Research Award, Duke University, Pratt School of Engineering, 2005

Courses Taught:
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 570L: Introduction to Biomolecular Engineering (GE, BB, MC)
  • BME 701S: BME Graduate Seminars
  • BME 702S: BME Graduate Seminars
  • BME 899: Special Readings in Biomedical Engineering
  • EGR 491: Projects in Engineering

Representative Publications: (More Publications)
    • Tang, L; Tjong, V; Li, N; Yingling, YG; Chilkoti, A; Zauscher, S, Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles., Advanced Materials, vol 26 no. 19 (2014), pp. 3050-3054 [10.1002/adma.201306049] [abs].
    • McDaniel, JR; MacEwan, SR; Li, X; Radford, DC; Landon, CD; Dewhirst, M; Chilkoti, A, Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 14 no. 5 (2014), pp. 2890-2895 [10.1021/nl5009376] [abs].
    • Tjong, V; Tang, L; Zauscher, S; Chilkoti, A, "Smart" DNA interfaces., Chemical Society Reviews, vol 43 no. 5 (2014), pp. 1612-1626 [10.1039/c3cs60331h] [abs].
    • Mastria, E; Chilkoti, A, Genetically encoded “smart” peptide polymers for biomedicine, Materials Research Society (MRS) Bulletin, vol 39 no. 01 (2014), pp. 35-43 [10.1557/mrs.2013.313] [abs].
    • Qi, Y; Chilkoti, A, Growing polymers from peptides and proteins: A biomedical perspective, Polymer Chemistry, vol 5 no. 2 (2014), pp. 266-276 [abs].