David Needham

Publications

Papers Published

  1. C. M. Yang and D. Plackett and D. Needham and H. M. Burt, PLGA and PHBV Microsphere Formulations and Solid-State Characterization: Possible Implications for Local Delivery of Fusidic Acid for the Treatment and Prevention of Orthopaedic Infections, Pharmaceutical Research, vol 26 no. 7 (2009), pp. 1644 -- 1656 [abs].
  2. J. A. Tashjian and M. W. Dewhirst and D. Needham and B. L. Viglianti, Rationale for and measurement of liposomal drug delivery with hyperthermia using non-invasive imaging techniques, International Journal Of Hyperthermia, vol 24 no. 1 (2008), pp. 79 -- 90 [abs].
  3. Q. Chen and A. Krol and A. Wright and D. Needham and M. W. Dewhirst and F. Yuan, Tumor microvascular permeability is a key determinant for antivascular effects of doxorubicin encapsulated in a temperature sensitive liposome, International Journal Of Hyperthermia, vol 24 no. 6 (2008), pp. 475 -- 482 [abs].
  4. B. L. Montalvo-ortiz and B. Sosa and D. Velez and D. Needham and K. Griebenow, Novel encapsulation of partially dehydrated protein microparticles in PLGA microspheres, Journal Of Biotechnology, vol 131 no. 2 (2007), pp. S51 -- S52.
  5. M. A. Holden and D. Needham and H. Bayley, Functional bionetworks from nanoliter water droplets, Journal Of The American Chemical Society, vol 129 no. 27 (2007), pp. 8650 -- 8655 [abs].
  6. S. I. Simon and T. Nyunt and K. Florine-casteel and K. Ritchie and H. P. Ting-beall and E. Evans and D. Needham, Dynamics of neutrophil membrane compliance and microstructure probed with a micropipet-based piconewton force transducer, Annals Of Biomedical Engineering, vol 35 no. 4 (2007), pp. 595 -- 604 [abs].
  7. M. Holden, D. Needham, H Bayley, Functional Bio-Networks from Nanoliter Water Droplets, J. Am Chem Soc., vol 129 (2007), pp. 8650-8655 [abs].
  8. S. I. Simon, K. Florine-Casteel, K. Ritchie, H.P. Ting-Beall, E. Evans, and D. Needham, Dynamics of Neutrophil Membrane Compliance and Microstructure probed with a Micropipet-based Piconewton Force Transducer, Annals Biomed Egr., vol 35 no. 4 (2007), pp. 595-604.
  9. A. M. Ponce and A. Wright and M. W. Dewhirts and D. Needham, Targeted bioavailability of drugs by triggered release from liposomes, Future Lipidology, vol 1 no. 1 (2006), pp. 25 -- 34 [abs].
  10. Mills, J.K. and Needham, D., Temperature-triggered nanotechnology for chemotherapy: Rapid release from lysolipid temperature-sensitive liposomes, 2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings, vol 2 (2006), pp. 5 - 8 [abs].
  11. Duncan, P. Brent and Needham, David, Microdroplet dissolution into a second-phase solvent using a micropipet technique: Test of the epstein-plesset model for an aniline-water system, Langmuir, vol 22 no. 9 (2006), pp. 4190 - 4197 [la053314e] [abs].
  12. D. Needham and A. M. Ponce, Nanoscale Drug Delivery Vehicles for Solid Tumors: A New Paradigm for Localized Drug Delivery (2006).
  13. Ponce, A.M. and Vujaskovic, Z. and Yuan, F. and Needham, D. and Dewhirst, M.W., Hyperthermia mediated liposomal drug delivery, Int. J. Hyperth. (UK), vol 22 no. 3 (2006), pp. 205 - 13 [02656730600582956] [abs].
  14. Needham, D.J. and Leach, J.A. and Merkin, J.H., The effects of a complexation reaction on travelling wave-fronts in a quadratic autocatalytic system, Q. J. Mech. Appl. Math. (UK), vol 58 (2005), pp. 577 - 99 [hbi022] [abs].
  15. Merkin, J.H. and Needham, D.J. and Sleeman, B.D., A mathematical model for the spread of morphogens with density dependent chemosensitivity, Nonlinearity (UK), vol 18 no. 6 (2005), pp. 2745 - 73 [018] [abs].
  16. Needham, D.J. and Leach, J.A. and Merkin, J.H., The effects of a complexation reaction on travelling wave-fronts in a quadratic autocatalytic system, Quarterly Journal of Mechanics and Applied Mathematics, vol 58 no. 4 (2005), pp. 577 - 599 [hbi022] [abs].
  17. Eichenbaum, Kenneth D. and Thomas, Allen A. and Eichenbaum, Gary M. and Gibney, Brian R. and Needham, David and Kiser, Patrick F., Oligo-α-hydroxy ester cross-linkers: Impact of cross-linker structure on biodegradable hydrogel networks, Macromolecules, vol 38 no. 26 (2005), pp. 10757 - 10762 [ma0518306] [abs].
  18. Duncan, P. Brent and Needham, David, Test of the Epstein-Plesset model for gas microparticle dissolution in aqueous media: Effect of surface tension and gas undersaturation in solution, Langmuir, vol 20 no. 7 (2004), pp. 2567 - 2578 [la034930i] [abs].
  19. Needham, David, Lipid Membranes: Biological Inspiration for Micro and Nano Encapsulation Technologies, Especially Drug Delivery, Materials Research Society Symposium - Proceedings, vol 774 (2003), pp. 173 - 202 [abs].
  20. Kim, Dennis H. and Costello, M. Joseph and Duncan, P. Brent and Needham, David, Mechanical properties and microstructure of polycrystalline phospholipid monolayer shells: Novel solid microparticles, Langmuir, vol 19 no. 20 (2003), pp. 8455 - 8466 [la034779c] [abs].
  21. Hasik, Matthew J. and Kim, Dennis H. and Howle, Laurens E. and Needham, David and Prush, Donald P., Evaluation of synthetic phospholipid ultrasound contrast agents, Ultrasonics, vol 40 no. 9 (2002), pp. 973 - 982 [S0041-624X(02)00384-0] [abs].
  22. Eichenbaum, Gary M. and Kiser, Patrick F. and Dobrynin, Andrey V. and Simon, Sidney A. and Needham, David, Erratum: Investigation of the swelling response and loading of ionic microgels with drugs and proteins; The dependence on cross-link density (Macromolecules (July 27, 1999) 32:15 (4867-4878)), Macromolecules, vol 34 no. 18 (2001), pp. 6526 - [ma0124892].
  23. Eichenbaum, Gary M. and Kiser, Patrick F. and Simon, Sidney A. and Needham, David, Erratum: pH and ion-triggered volume responses of anionic hydrogel microspheres (Macromolecules (July 28, 1998) 31:15 (5084-5093)), Macromolecules, vol 34 no. 20 (2001), pp. 7230 - [ma012488+].
  24. Lee, Sunghee and Kim, Dennis H. and Needham, David, Equilibrium and dynamic interfacial tension measurements at microscopic interfaces using a micropipet technique - 2. Dynamics of phospholipid monolayer formation and equilibrium tensions at the water-air interface, Langmuir, vol 17 no. 18 (2001), pp. 5544 - 5550 [la0103261] [abs].
  25. Needham, D. and Dewhirst, M.W., The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors, Advanced Drug Delivery Reviews, vol 53 no. 3 (2001), pp. 285 - 305 [S0169-409X(01)00233-2] [abs].
  26. Lee, Sunghee and Kim, Dennis H. and Needham, David, Equilibrium and dynamic interfacial tension measurements at microscopic interfaces using a micropipet technique. 1: A new method for determination of interracial tension, Langmuir, vol 17 no. 18 (2001), pp. 5537 - 5543 [la0103259] [abs].
  27. Kiser, Patrick F. and Thomas, Allen A. and Eichenbaum, Gary M. and Needham, David and Kim, Intae, Design and performance of poly(HPMA) hydrogels containing symmetrical biodegradable crosslinkers composed of oligo-lactate and oligo-glycolate esters, American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, vol 41 no. 1 (2000), pp. 712 - 713 [abs].
  28. Kim, Dennis H. and Klibanov, Alexander L. and Needham, David, Influence of tiered layers of surface-grafted poly(ethylene glycol) on receptor-ligand-mediated adhesion between phospholipid monolayer-stabilized microbubbles and coated glass beads, Langmuir, vol 16 no. 6 (2000), pp. 2808 - 2817 [la990749r] [abs].
  29. Needham, David and Kim, Dennis H., PEG-covered lipid surfaces: Bilayers and monolayers, Colloids and Surfaces B: Biointerfaces, vol 18 no. 3 (2000), pp. 183 - 195 [S0927-7765(99)00147-2] [abs].
  30. Eichenbaum, Gary M. and Kiser, Patrick F. and Shah, Dipak and Meuer, William P. and Needham, David and Simon, Sidney A., Alkali earth metal binding properties of ionic microgels, Macromolecules, vol 33 no. 11 (2000), pp. 4087 - 4093 [ma9917139] [abs].
  31. Olbrich, K. and Rawicz, W. and Needham, D. and Evans, E., Water permeability and mechanical strength of polyunsaturated lipid bilayers, Biophys. J. (USA), vol 79 no. 1 (2000), pp. 321 - 7 [abs].
  32. Rawicz, W. and Olbrich, K.C. and McIntosh, T. and Needham, D. and Evans, E., Effect of chain length and unsaturation on elasticity of lipid bilayers, Biophys. J. (USA), vol 79 no. 1 (2000), pp. 328 - 39 [abs].
  33. Needham, D. and Demurjian, S. and Peters, T., An IDL to Ada95 mapping to support propagation modeling, Ada Lett. (USA), vol 20 no. 1 (2000), pp. 58 - 66 [abs].
  34. Needham, David, Materials engineering of lipid bilayers for drug carrier performance, MRS Bulletin, vol 24 no. 10 (1999), pp. 32 - 40 [abs].
  35. Eichenbaum, Gary M. and Kiser, Patrick F. and Shah, Dipak and Simon, Sidney A. and Needham, David, Investigation of the swelling response and drug loading of ionic microgels: The dependence on functional group composition, Macromolecules, vol 32 no. 26 (1999), pp. 8996 - 9006 [ma9908393] [abs].
  36. Eichenbaum, Gary M. and Kiser, Patrick F. and Dobrynin, Andrey V. and Simon, Sidney A. and Needham, David, Investigation of the swelling response and loading of ionic microgels with drugs and proteins: the dependence on cross-link density, Macromolecules, vol 32 no. 15 (1999), pp. 4867 - 4878 [ma981945s] [abs].
  37. Eichenbaum, Gary M. and Kiser, Patrick F. and Simon, Sidney A. and Needham, David, pH and ion-triggered volume response of anionic hydrogel microspheres, Macromolecules, vol 31 no. 15 (1998), pp. 5084 - 5093 [ma970897t] [abs].
  38. Kiser, Patrick F. and Wilson, Glynn and Needham, David, Synthetic mimic of the secretory granule for drug delivery, Nature, vol 394 no. 6692 (1998), pp. 459 - 462 [28822] [abs].
  39. Needham, D.J. and McAllister, S., Centre families in two-dimensional complex holomorphic dynamical systems, Proc. R. Soc. Lond. A, Math. Phys. Eng. Sci. (UK), vol 454 no. 1976 (1998), pp. 2267 - 78 [0258] [abs].
  40. Kiser, Patrick F. and Needham, David and Wilson, Glynn, Mimicking the smart polymer matrix of the secretory granule: a new concept in controlled release drug delivery, Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, vol 76 (1997), pp. 226 - [abs].
  41. Needham, David and Noppl-Simson, Doris, Barrier properties of surface-grafted PEG for macromolecule-surface interactions, American Chemical Society, Polymer Priprints, Division of Polymer Chemistry, vol 38 no. 1 (1997), pp. 549 - 550 [abs].
  42. Evans, E. and Bowman, H. and Leung, A. and Needham, D. and Tirrell, D., Biomembrane templates for nanoscale conduits and networks, Science, vol 273 no. 5277 (1996), pp. 933 -.
  43. Bowman, H. and Evans, E. and Needham, D. and Tirrell, D.A., Nanometer-scale polymeric patterns and networks, Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, vol 74 (1996), pp. 437 -.
  44. Zhelev, Doncho V. and Needham, David, Pore formation and pore dynamics in bilayer membranes, American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD, vol 337 (1996), pp. 47 - 49 [abs].
  45. Noppl-Simson, D. A. and Needham, D., Avidin-biotin interactions at vesicle surfaces: adsorption and binding, cross-bridge formation, and lateral interactions, Biophysical Journal, vol 70 no. 3 (1996), pp. 1391 -.
  46. Needham, D.J. and King, A.C. and Merkin, J.H., Reaction-diffusion model for autocatalytic polymerization: II. The initial value problem, IMA Journal of Applied Mathematics (Institute of Mathematics & Its Applications), vol 56 no. 1 (1996), pp. 65 - 86 [abs].
  47. Hristova, K. and Needham, D., Influence of bilayer fluctuations on the steric interactions between polymer-grafted bilayers, Liquid Crystals, vol 18 no. 3 (1995), pp. 423 -.
  48. Needham, D.J., Centre theorem for two-dimensional complex holomorphic systems and its generalization, Proceedings of The Royal Society of London, Series A: Mathematical and Physical Sciences, vol 450 no. 1939 (1995), pp. 225 - 232.
  49. Hristova, Kalina and Needham, David, Phase behavior of a lipid/polymer-lipid mixture in aqueous medium, Macromolecules, vol 28 no. 4 (1995), pp. 991 - 1002 [abs].
  50. Needham, D. and Zhelev, D.V., Lysolipid exchange with vesicle membranes and the formation and evolution of porous defects, Annals of Biomedical Engineering, vol 23 no. 3 (1995), pp. 287 -.
  51. Lasic, Danilo D. and Needham, David, `Stealth' liposome: A prototypical biomaterial, Chemical Reviews, vol 95 no. 8 (1995), pp. 2601 -.
  52. Needham, David and Noppl, Doris, Adsorption and adhesion at vesicle surfaces: the influence of grafted polymer on avidin-biotin binding and tests of receptor-mediated adhesion, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol 29 (1995), pp. 331 - 332 [abs].
  53. Kenworthy, A.K. and Hristova, K. and Needham, D. and McIntosh, T.J., Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol), Biophys. J. (USA), vol 68 no. 5 (1995), pp. 1921 - 36 [abs].
  54. Hristova, Kalina and Needham, David, Influence of polymer-grafted lipids on the physical properties of lipid bilayers: A theoretical study, Journal of Colloid and Interface Science, vol 168 no. 2 (1994), pp. 302 - 314 [1424] [abs].
  55. Zhelev, D.V. and Needham, D. and Hochmuth, R.M., Role of the membrane cortex in neutrophil deformation in small pipets, Biophys. J. (USA), vol 67 no. 2 (1994), pp. 696 - 705 [abs].
  56. Zhelev, D.V. and Needham, D. and Hochmuth, R.M., A novel micropipet method for measuring the bending modulus of vesicle membranes, Biophys. J. (USA), vol 67 no. 2 (1994), pp. 720 - 7 [abs].
  57. Hochmuth, R.M. and Ting-Beall, H.P. and Beaty, B.B. and Needham, D. and Tran-Son-Tay, R., Viscosity of passive human neutrophils undergoing small deformations, Biophys. J. (USA), vol 64 no. 5 (1993), pp. 1596 - 601 [abs].
  58. Needham, D.J., Formal theory concerning the generation and propagation of travelling wave-fronts in reaction-diffusion equations, Quarterly Journal of Mechanics and Applied Mathematics, vol 45 no. pt 3 (1992), pp. 469 - 498 [abs].
  59. Needham, D. and Hochmuth, R.M., A sensitive measure of surface stress in the resting neutrophil, Biophys. J. (USA), vol 61 no. 6 (1992), pp. 1664 - 70 [abs].
  60. Simon, S.A. and McIntosh, T.J. and Magid, A.D. and Needham, D., Modulation of the interbilayer hydration pressure by the addition of dipoles at the hydrocarbon/water interface, Biophys. J. (USA), vol 61 no. 3 (1992), pp. 786 - 99 [abs].
  61. Tran-Son-Tay, R. and Needham, D. and Yeung, A. and Hochmuth, R.M., Time-dependent recovery of passive neutrophils after large deformation, Biophys. J. (USA), vol 60 no. 4 (1991), pp. 856 - 66 [abs].
  62. Needham, D. and Ting-Beall, H.P. and Tran-Son-Tay, R., Physical characterization of GAP A3 hybridoma cells. Morphology, geometry, and mechanical properties, Biotechnology and Bioengineering, vol 38 no. 8 (1991), pp. 838 - 852 [abs].
  63. Tran-Son-Tay, R. and Needham, D. and Hochmuth, R.M., Recovery of passive neutrophils after large deformation. Liquid drop model, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol 20 (1991), pp. 421 - 424 [abs].
  64. Hochmuth, R.M. and Needham, D. and Ting-Beall, H.P. and Zhelev, D., Deformation and flow of neutrophils in micropipets, Annals of Biomedical Engineering, vol 19 no. 5 (1991), pp. 568 - [abs].
  65. Needham, D., Morphology, geometry and mechanical properties of GAP A3 hybridoma cells as a function of the cell cycle, Annals of Biomedical Engineering, vol 19 no. 5 (1991), pp. 592 - 593 [abs].
  66. Hochmuth, R.M. and Needham, D. and Ting-Beall, H.P., Deformation and flow of neutrophils and monocytes, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol 20 (1991), pp. 417 - 419 [abs].
  67. Needham, D. and McIntosh, T.J., Mechanical and interactive properties of lipid membranes containing surface-bound polymer, Annals of Biomedical Engineering, vol 19 no. 5 (1991), pp. 593 - [abs].
  68. Needham, D. and Nunn, R.S., Elastic deformation and failure of lipid bilayer membranes containing cholesterol, Biophys. J. (USA), vol 58 no. 4 (1990), pp. 997 - 1009 [abs].
  69. Needham, D. and Hochmuth, R.M., Rapid flow of passive neutrophils into a 4 μm pipet and measurement of cytoplasmic viscosity, Journal of Biomechanical Engineering, Transactions of the ASME, vol 112 no. 3 (1990), pp. 269 - 276 [abs].
  70. Needham, D. and Ting-Beall, H.P. and Tran-Son-Tay, R., Morphology and mechanical properties of gap A3 hybridoma cells as related to cell cycle, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol 16 (1990), pp. 5 - 10 [abs].
  71. Hochmuth, R.M. and Needham, D. and Ting-Beall, H.P., Deformation and flow of neutrophils and monocytes, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol 20 (1990), pp. 417 - 419 [abs].
  72. Tran-Son-Tay, R. and Needham, D. and Hochmuth, R.M., Recovery of passive neutrophils after large deformation. Liquid drop model, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol 20 (1990), pp. 421 - 424 [abs].
  73. Hochmuth, R.M. and Needham, D., The viscosity of neutrophils and their transit times through small pores, Biorheology (UK), vol 27 no. 6 (1990), pp. 817 - 28 [abs].
  74. Needham, D. and Hochmuth, R.M., Electro-mechanical permeabilization of lipid vesicles. Role of membrane tension and compressibility, Biophys. J. (USA), vol 55 no. 5 (1989), pp. 1001 - 9 [abs].
  75. Evans, E. and Needham, D., ATTRACTION BETWEEN LIPID BILAYER MEMBRANES IN CONCENTRATED SOLUTIONS OF NONADSORBING POLYMERS: COMPARISON OF MEAN-FIELD THEORY WITH MEASUREMENTS OF ADHESION ENERGY., Macromolecules, vol 21 no. 6 (1988), pp. 1822 - 1831 [abs].
  76. Evans, E. and Needham, D., Physical properties of surfactant bilayer membranes: thermal transitions, elasticity, rigidity, cohesion, and colloidal interactions, J. Phys. Chem. (USA), vol 91 no. 16 (1987), pp. 4219 - 28 [abs].
  77. Elliott, J.R. and Haydon, D.A. and Hendry, B.M. and Needham, D., Inactivation of the sodium current in squid giant axons by hydrocarbons, Biophys. J. (USA), vol 48 no. 4 (1985), pp. 617 - 22 [abs].
  78. Eley, D. D. and Needham, D., HYDRIDIZATION AND CATALYSIS BY LANTHANIDE FILMS., Proceedings of The Royal Society of London, Series A: Mathematical and Physical Sciences, vol 393 no. 1805 (1984), pp. 257 - 276 [abs].
  79. Needham, D. and Haydon, D.A., Tensions and free energies of formation of `solventless' lipid bilayers. Measurement of high contact angles, Biophys. J. (USA), vol 41 no. 3 (1983), pp. 251 - 7 [abs].