Ashutosh Chilkoti

Publications

  • Li, NK; García Quiroz, F; Hall, CK; Chilkoti, A; Yingling, YG, Molecular description of the LCST behavior of an elastin-like polypeptide., Biomacromolecules, vol 15 no. 10 (2014), pp. 3522-3530 [10.1021/bm500658w] [abs].
  • Macewan, SR; Chilkoti, A, Applications of elastin-like polypeptides in drug delivery, Journal of Controlled Release, vol 190 (2014), pp. 314-330 [10.1016/j.jconrel.2014.06.028] [abs].
  • MacEwan, SR; Chilkoti, A, Applications of elastin-like polypeptides in drug delivery., Journal of Controlled Release, vol 190 (2014), pp. 314-330 [10.1016/j.jconrel.2014.06.028] [abs].
  • Yousefpour, P; Chilkoti, A, Co-opting biology to deliver drugs., Biotechnology and Bioengineering, vol 111 no. 9 (2014), pp. 1699-1716 [10.1002/bit.25307] [abs].
  • Ghoorchian, A; Chilkoti, A; López, GP, Simple assay for proteases based on aggregation of stimulus-responsive polypeptides., Analytical Chemistry, vol 86 no. 12 (2014), pp. 6103-6110 [10.1021/ac5012574] [abs].
  • Tang, L; Tjong, V; Li, N; Yingling, YG; Chilkoti, A; Zauscher, S, Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles, Advanced Materials, vol 26 no. 19 (2014), pp. 3050-3054 [10.1002/adma.201306049] [abs].
  • McDaniel, JR; MacEwan, SR; Li, X; Radford, DC; Landon, CD; Dewhirst, M; Chilkoti, A, Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 14 no. 5 (2014), pp. 2890-2895 [10.1021/nl5009376] [abs].
  • Tang, L; Tjong, V; Li, N; Yingling, YG; Chilkoti, A; Zauscher, S, Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles., Advanced Materials, vol 26 no. 19 (2014), pp. 3050-3054 [10.1002/adma.201306049] [abs].
  • MacEwan, SR; Chilkoti, A, Controlled apoptosis by a thermally toggled nanoscale amplifier of cellular uptake., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 14 no. 4 (2014), pp. 2058-2064 [10.1021/nl5002313] [abs].
  • Tjong, V; Tang, L; Zauscher, S; Chilkoti, A, "Smart" DNA interfaces., Chemical Society Reviews, vol 43 no. 5 (2014), pp. 1612-1626 [10.1039/c3cs60331h] [abs].
  • Qi, Y; Chilkoti, A, Growing polymers from peptides and proteins: A biomedical perspective, Polymer Chemistry, vol 5 no. 2 (2014), pp. 266-276 [10.1039/c3py01089a] [abs].
  • Mastria, E; Chilkoti, A, Genetically encoded “smart” peptide polymers for biomedicine, Materials Research Society (MRS) Bulletin, vol 39 no. 01 (2014), pp. 35-43 [10.1557/mrs.2013.313] [abs].
  • MacEwan, SR; Hassouneh, W; Chilkoti, A, Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli., Journal of Visualized Experiments no. 88 (2014) [10.3791/51583] [abs].
  • MacEwan, SR; Hassouneh, W; Chilkoti, A, Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli., Journal of Visualized Experiments no. 88 (2014) [abs].
  • Yousefpour, P; Chilkoti, A, Co-opting biology to deliver drugs, Biotechnology and Bioengineering, vol 111 no. 9 (2014), pp. 1699-1716 [10.1002/bit.25307] [abs].
  • Amiram, M; Luginbuhl, KM; Li, X; Feinglos, MN; Chilkoti, A, A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection., Journal of Controlled Release, vol 172 no. 1 (2013), pp. 144-151 [10.1016/j.jconrel.2013.07.021] [abs].
  • Sinclair, SM; Bhattacharyya, J; McDaniel, JR; Gooden, DM; Gopalaswamy, R; Chilkoti, A; Setton, LA, A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation., Journal of Controlled Release, vol 171 no. 1 (2013), pp. 38-47 [10.1016/j.jconrel.2013.06.032] [abs].
  • McDaniel, JR; Dewhirst, MW; Chilkoti, A, Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia., International Journal of Hyperthermia, vol 29 no. 6 (2013), pp. 501-510 [10.3109/02656736.2013.819999] [abs].
  • Khan, MN; Tjong, V; Chilkoti, A; Zharnikov, M, Spectroscopic study of a DNA brush synthesized in situ by surface initiated enzymatic polymerization., The Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces and Biophysical, vol 117 no. 34 (2013), pp. 9929-9938 [10.1021/jp404774x] [abs].
  • McDaniel, JR; Radford, DC; Chilkoti, A, A unified model for de novo design of elastin-like polypeptides with tunable inverse transition temperatures., Biomacromolecules, vol 14 no. 8 (2013), pp. 2866-2872 [10.1021/bm4007166] [abs].
  • Qi, Y; Amiram, M; Gao, W; McCafferty, DG; Chilkoti, A, Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein., Macromolecular Rapid Communications, vol 34 no. 15 (2013), pp. 1256-1260 [10.1002/marc.201300460] [abs].
  • Kurzbach, D; Hassouneh, W; McDaniel, JR; Jaumann, EA; Chilkoti, A; Hinderberger, D, Hydration layer coupling and cooperativity in phase behavior of stimulus responsive peptide polymers., Journal of the American Chemical Society, vol 135 no. 30 (2013), pp. 11299-11308 [10.1021/ja4047872] [abs].
  • Hassouneh, W; Nunalee, ML; Shelton, MC; Chilkoti, A, Calcium binding peptide motifs from calmodulin confer divalent ion selectivity to elastin-like polypeptides., Biomacromolecules, vol 14 no. 7 (2013), pp. 2347-2353 [10.1021/bm400464s] [abs].
  • Christensen, T; Hassouneh, W; Trabbic-Carlson, K; Chilkoti, A, Predicting transition temperatures of elastin-like polypeptide fusion proteins., Biomacromolecules, vol 14 no. 5 (2013), pp. 1514-1519 [10.1021/bm400167h] [abs].
  • Bellucci, JJ; Amiram, M; Bhattacharyya, J; McCafferty, D; Chilkoti, A, Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides., Angewandte Chemie International Edition, vol 52 no. 13 (2013), pp. 3703-3708 [10.1002/anie.201208292] [abs].
  • Amiram, M; Luginbuhl, KM; Li, X; Feinglos, MN; Chilkoti, A, Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control., Proceedings of the National Academy of Sciences of USA, vol 110 no. 8 (2013), pp. 2792-2797 [10.1073/pnas.1214518110] [abs].
  • McDaniel, JR; Bhattacharyya, J; Vargo, KB; Hassouneh, W; Hammer, DA; Chilkoti, A, Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation., Angewandte Chemie International Edition, vol 52 no. 6 (2013), pp. 1683-1687 [10.1002/anie.201200899] [abs].
  • Tjong, V; Yu, H; Hucknall, A; Chilkoti, A, Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization., Analytical Chemistry, vol 85 no. 1 (2013), pp. 426-433 [10.1021/ac303132j] [abs].
  • Li, L; Im, O; Chilkoti, A; López, GP,
    Encapsulation of Stimuli-Responsive Fusion Proteins in Silica: Thermally Responsive Metal Ion-Sensitive Hybrid Membranes
    , MRS Online Proceedings Library, vol 1498 (2013) [10.1557/opl.2013.332] [abs].
  • MacEwan, SR; Chilkoti, A, Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents., Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, vol 5 no. 1 (2013), pp. 31-48 [10.1002/wnan.1197] [abs].
  • Thapa, A; Han, W; Simons, RH; Chilkoti, A; Chi, EY; López, GP, Effect of detergents on the thermal behavior of elastin-like polypeptides., Biopolymers, vol 99 no. 1 (2013), pp. 55-62 [10.1002/bip.22137] [abs].
  • Lassiter, JB; McGuire, F; Mock, JJ; Ciracì, C; Hill, RT; Wiley, BJ; Chilkoti, A; Smith, DR, Plasmonic waveguide modes of film-coupled metallic nanocubes., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 13 no. 12 (2013), pp. 5866-5872 [10.1021/nl402660s] [abs].
  • Qi, Y; Amiram, M; Gao, W; McCafferty, DG; Chilkoti, A, Sortase-Catalyzed Initiator Attachment Enables High Yield Growth of a Stealth Polymer from the C Terminus of a Protein, Macromolecular Rapid Communications, vol 34 no. 15 (2013), pp. 1256-1260 [10.1002/marc.201300460] [abs].
  • Tjong, V; Yu, H; Hucknall, A; Chilkoti, A, Amplified fluorescence detection of DNA and RNA hybridization by surface initiated enzymatic polymerization (SIEP), Technical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013, vol 3 (2013), pp. 32-36 [abs].
  • Weller, D; McDaniel, JR; Fischer, K; Chilkoti, A; Schmidt, M, Cylindrical polymer brushes with elastin-like polypeptide side chains, Macromolecules, vol 46 no. 12 (2013), pp. 4966-4971 [10.1021/ma400917t] [abs].
  • Moreau, A; Ciracì, C; Mock, JJ; Hill, RT; Wang, Q; Wiley, BJ; Chilkoti, A; Smith, DR, Controlled-reflectance surfaces with film-coupled colloidal nanoantennas., Nature, vol 492 no. 7427 (2012), pp. 86-89 [10.1038/nature11615] [abs].
  • Liu, W; McDaniel, J; Li, X; Asai, D; Quiroz, FG; Schaal, J; Park, JS; Zalutsky, M; Chilkoti, A, Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ., Cancer Research, vol 72 no. 22 (2012), pp. 5956-5965 [10.1158/0008-5472.CAN-12-2127] [abs].
  • Manzoor, AA; Lindner, LH; Landon, CD; Park, JY; Simnick, AJ; Dreher, MR; Das, S; Hanna, G; Park, W; Chilkoti, A; Koning, GA; ten Hagen, TL; Needham, D; Dewhirst, MW, Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors., Cancer Research, vol 72 no. 21 (2012), pp. 5566-5575 [10.1158/0008-5472.CAN-12-1683] [abs].
  • Hill, RT; Mock, JJ; Hucknall, A; Wolter, SD; Jokerst, NM; Smith, DR; Chilkoti, A, Plasmon ruler with angstrom length resolution., ACS Nano, vol 6 no. 10 (2012), pp. 9237-9246 [10.1021/nn3035809] [abs].
  • Khan, MN; Tjong, V; Chilkoti, A; Zharnikov, M, Fabrication of ssDNA/oligo(ethylene glycol) monolayers and complex nanostructures by an irradiation-promoted exchange reaction., Angewandte Chemie International Edition, vol 51 no. 41 (2012), pp. 10303-10306 [10.1002/anie.201204245] [abs].
  • Kwok, KW; Auffan, M; Badireddy, AR; Nelson, CM; Wiesner, MR; Chilkoti, A; Liu, J; Marinakos, SM; Hinton, DE, Uptake of silver nanoparticles and toxicity to early life stages of Japanese medaka (Oryzias latipes): effect of coating materials., Aquatic Toxicology, vol 120-121 (2012), pp. 59-66 [10.1016/j.aquatox.2012.04.012] [abs].
  • Ciracì, C; Hill, RT; Mock, JJ; Urzhumov, Y; Fernández-Domínguez, AI; Maier, SA; Pendry, JB; Chilkoti, A; Smith, DR, Probing the ultimate limits of plasmonic enhancement., Science, vol 337 no. 6098 (2012), pp. 1072-1074 [10.1126/science.1224823] [abs].
  • Xu, D; Asai, D; Chilkoti, A; Craig, SL, Rheological properties of cysteine-containing elastin-like polypeptide solutions and hydrogels., Biomacromolecules, vol 13 no. 8 (2012), pp. 2315-2321 [10.1021/bm300760s] [abs].
  • Hubbell, JA; Chilkoti, A, Chemistry. Nanomaterials for drug delivery., Science, vol 337 no. 6092 (2012), pp. 303-305 [10.1126/science.1219657] [abs].
  • Asai, D; Xu, D; Liu, W; Garcia Quiroz, F; Callahan, DJ; Zalutsky, MR; Craig, SL; Chilkoti, A, Protein polymer hydrogels by in situ, rapid and reversible self-gelation., Biomaterials, vol 33 no. 21 (2012), pp. 5451-5458 [10.1016/j.biomaterials.2012.03.083] [abs].
  • Macewan, SR; Chilkoti, A, Digital switching of local arginine density in a genetically encoded self-assembled polypeptide nanoparticle controls cellular uptake., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 12 no. 6 (2012), pp. 3322-3328 [10.1021/nl301529p] [abs].
  • Hassouneh, W; Fischer, K; MacEwan, SR; Branscheid, R; Fu, CL; Liu, R; Schmidt, M; Chilkoti, A, Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers., Biomacromolecules, vol 13 no. 5 (2012), pp. 1598-1605 [10.1021/bm300321n] [abs].
  • McDaniel, JR; Macewan, SR; Dewhirst, M; Chilkoti, A, Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia., Journal of Controlled Release, vol 159 no. 3 (2012), pp. 362-367 [10.1016/j.jconrel.2012.02.030] [abs].
  • Callahan, DJ; Liu, W; Li, X; Dreher, MR; Hassouneh, W; Kim, M; Marszalek, P; Chilkoti, A, Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 12 no. 4 (2012), pp. 2165-2170 [10.1021/nl300630c] [abs].
  • Mock, JJ; Hill, RT; Tsai, YJ; Chilkoti, A; Smith, DR, Probing dynamically tunable localized surface plasmon resonances of film-coupled nanoparticles by evanescent wave excitation., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 12 no. 4 (2012), pp. 1757-1764 [10.1021/nl204596h] [abs].
  • Tjong, V; Zhang, J; Chilkoti, A; Zauscher, S, Stimulus-Responsive Polymers as Intelligent Coatings for Biosensors: Architectures, Response Mechanisms, and Applications (2012), pp. 1-30 [10.1002/9781118181249.ch1] [abs].
  • Christensen, T; Hassouneh, W; Callahan, DJ; Chilkoti, A, Protein switches, Comprehensive Biophysics, vol 3 (2012), pp. 238-266 [10.1016/B978-0-12-374920-8.00316-7] [abs].
  • Hassouneh, W; MacEwan, SR; Chilkoti, A, Fusions of elastin-like polypeptides to pharmaceutical proteins., Methods in Enzymology, vol 502 (2012), pp. 215-237 [10.1016/B978-0-12-416039-2.00024-0] [abs].
  • Ferris, R; Hucknall, A; Kwon, BS; Chen, T; Chilkoti, A; Zauscher, S, Field-induced nanolithography for patterning of non-fouling polymer brush surfaces., Small, vol 7 no. 21 (2011), pp. 3032-3037 [10.1002/smll.201100923] [abs].
  • Seekell, K; Crow, MJ; Marinakos, S; Ostrander, J; Chilkoti, A; Wax, A, Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles., Journal of Biomedical Optics, vol 16 no. 11 (2011) [10.1117/1.3646529] [abs].
  • Simnick, AJ; Amiram, M; Liu, W; Hanna, G; Dewhirst, MW; Kontos, CD; Chilkoti, A, In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide., Journal of Controlled Release, vol 155 no. 2 (2011), pp. 144-151 [10.1016/j.jconrel.2011.06.044] [abs].
  • Nusz, GJ; Marinakos, SM; Rangarajan, S; Chilkoti, A, Dual-order snapshot spectral imaging of plasmonic nanoparticles., Applied Optics, vol 50 no. 21 (2011), pp. 4198-4206 [abs].
  • Tjong, V; Yu, H; Hucknall, A; Rangarajan, S; Chilkoti, A, Amplified on-chip fluorescence detection of DNA hybridization by surface-initiated enzymatic polymerization., Analytical Chemistry, vol 83 no. 13 (2011), pp. 5153-5159 [10.1021/ac200946t] [abs].
  • Fluegel, S; Buehler, J; Fischer, K; McDaniel, JR; Chilkoti, A; Schmidt, M, Self-assembly of monodisperse oligonucleotide-elastin block copolymers into stars and compound micelles., Chemistry: A European Journal, vol 17 no. 20 (2011), pp. 5503-5506 [10.1002/chem.201100436] [abs].
  • Ahmad, SA; Leggett, GJ; Hucknall, A; Chilkoti, A, Micro- and nanostructured poly[oligo(ethylene glycol)methacrylate] brushes grown from photopatterned halogen initiators by atom transfer radical polymerization., Biointerphases: an open access journal for the biomaterials interface community, vol 6 no. 1 (2011), pp. 8-15 [10.1116/1.3553579] [abs].
  • Yang, P; Marinakos, SM; Chilkoti, A, Spatially addressable chemoselective C-terminal ligation of an intein fusion protein from a complex mixture to a hydrazine-terminated surface., Langmuir: the ACS journal of surfaces and colloids, vol 27 no. 4 (2011), pp. 1463-1471 [10.1021/la104186n] [abs].
  • Amiram, M; Quiroz, FG; Callahan, DJ; Chilkoti, A, A highly parallel method for synthesizing DNA repeats enables the discovery of 'smart' protein polymers., Nature Materials, vol 10 no. 2 (2011), pp. 141-148 [10.1038/nmat2942] [abs].
  • Crow, MJ; Marinakos, SM; Cook, JM; Chilkoti, A; Wax, A, Plasmonic flow cytometry by immunolabeled nanorods., Cytometry Part A, vol 79 no. 1 (2011), pp. 57-65 [10.1002/cyto.a.20994] [abs].
  • Williams, C; Brown, XQ; Bartolak-Suki, E; Ma, H; Chilkoti, A; Wong, JY, The use of micropatterning to control smooth muscle myosin heavy chain expression and limit the response to transforming growth factor β1 in vascular smooth muscle cells., Biomaterials, vol 32 no. 2 (2011), pp. 410-418 [10.1016/j.biomaterials.2010.08.105] [abs].
  • Ahmad, SA; Leggett, GJ; Hucknall, A; Chilkoti, A, Micro- and nanostructured poly[oligo(ethylene glycol)methacrylate] brushes grown from photopatterned halogen initiators by atom transfer radical polymerization., Biointerphases: an open access journal for the biomaterials interface community, vol 6 no. 1 (2011), pp. 8-15 [10.1116/1.3553579] [abs].
  • Chen, S-Y; Mock, JJ; Hill, RT; Chilkoti, A; Smith, DR; Lazarides, AA, Raman antenna formed by molecule/plasmonic nanostructure hybrid system (2011) [abs].
  • Chen, SY; Mock, JJ; Hill, RT; Chilkoti, A; Smith, DR; Lazarides, AA, Raman antenna formed by molecule/plasmonic nanostructure hybrid system, 2011 Conference on Lasers and Electro-Optics: Laser Science to Photonic Applications, CLEO 2011 (2011) [abs].
  • Crow, MJ; Seekell, K; Marinakos, S; Ostrander, J; Chilkoti, A; Wax, AP, Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles, Proceedings of SPIE, vol 7911 (2011) [10.1117/12.874093] [abs].
  • Gao, W; Xu, D; Lim, DW; Craig, SL; Chilkoti, A, In situ growth of a thermoresponsive polymer from a genetically engineered elastin-like polypeptide, Polymer Chemistry, vol 2 no. 7 (2011), pp. 1561-1566 [10.1039/c1py00074h] [abs].
  • McDaniel, JR; Callahan, DJ; Chilkoti, A, Drug delivery to solid tumors by elastin-like polypeptides., Advanced Drug Delivery Reviews, vol 62 no. 15 (2010), pp. 1456-1467 [10.1016/j.addr.2010.05.004] [abs].
  • Nettles, DL; Chilkoti, A; Setton, LA, Applications of elastin-like polypeptides in tissue engineering., Advanced Drug Delivery Reviews, vol 62 no. 15 (2010), pp. 1479-1485 [10.1016/j.addr.2010.04.002] [abs].
  • Chen, SY; Mock, JJ; Hill, RT; Chilkoti, A; Smith, DR; Lazarides, AA, Gold nanoparticles on polarizable surfaces as Raman scattering antennas., ACS Nano, vol 4 no. 11 (2010), pp. 6535-6546 [10.1021/nn101644s] [abs].
  • Fluegel, S; Fischer, K; McDaniel, JR; Chilkoti, A; Schmidt, M, Chain stiffness of elastin-like polypeptides., Biomacromolecules, vol 11 no. 11 (2010), pp. 3216-3218 [10.1021/bm100965y] [abs].
  • Mackay, JA; Callahan, DJ; Fitzgerald, KN; Chilkoti, A, Quantitative model of the phase behavior of recombinant pH-responsive elastin-like polypeptides., Biomacromolecules, vol 11 no. 11 (2010), pp. 2873-2879 [10.1021/bm100571j] [abs].
  • Meyer, JN; Lord, CA; Yang, XY; Turner, EA; Badireddy, AR; Marinakos, SM; Chilkoti, A; Wiesner, MR; Auffan, M, Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans., Aquatic Toxicology, vol 100 no. 2 (2010), pp. 140-150 [10.1016/j.aquatox.2010.07.016] [abs].
  • Hill, RT; Mock, JJ; Urzhumov, Y; Sebba, DS; Oldenburg, SJ; Chen, SY; Lazarides, AA; Chilkoti, A; Smith, DR, Leveraging nanoscale plasmonic modes to achieve reproducible enhancement of light., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 10 no. 10 (2010), pp. 4150-4154 [10.1021/nl102443p] [abs].
  • Gao, W; Liu, W; Christensen, T; Zalutsky, MR; Chilkoti, A, In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation., Proceedings of the National Academy of Sciences of USA, vol 107 no. 38 (2010), pp. 16432-16437 [10.1073/pnas.1006044107] [abs].
  • Hassouneh, W; Christensen, T; Chilkoti, A, Elastin-like polypeptides as a purification tag for recombinant proteins., Current Protocols in Protein Science, vol Chapter 6 (2010), pp. Unit-6.11 [10.1002/0471140864.ps0611s61] [abs].
  • MacEwan, SR; Callahan, DJ; Chilkoti, A, Stimulus-responsive macromolecules and nanoparticles for cancer drug delivery., Nanomedicine, vol 5 no. 5 (2010), pp. 793-806 [10.2217/nnm.10.50] [abs].
  • Alang Ahmad, S; Hucknall, A; Chilkoti, A; Leggett, GJ, Protein patterning by UV-induced photodegradation of poly(oligo(ethylene glycol) methacrylate) brushes., Langmuir: the ACS journal of surfaces and colloids, vol 26 no. 12 (2010), pp. 9937-9942 [10.1021/la100438d] [abs].
  • Jenness, NJ; Hill, RT; Hucknall, A; Chilkoti, A; Clark, RL, A versatile diffractive maskless lithography for single-shot and serial microfabrication., Optics Express, vol 18 no. 11 (2010), pp. 11754-11762 [abs].
  • Liu, W; MacKay, JA; Dreher, MR; Chen, M; McDaniel, JR; Simnick, AJ; Callahan, DJ; Zalutsky, MR; Chilkoti, A, Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model., Journal of Controlled Release, vol 144 no. 1 (2010), pp. 2-9 [10.1016/j.jconrel.2010.01.032] [abs].
  • Simnick, AJ; Valencia, CA; Liu, R; Chilkoti, A, Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer., ACS Nano, vol 4 no. 4 (2010), pp. 2217-2227 [10.1021/nn901732h] [abs].
  • McDaniel, JR; Mackay, JA; Quiroz, FG; Chilkoti, A, Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes., Biomacromolecules, vol 11 no. 4 (2010), pp. 944-952 [10.1021/bm901387t] [abs].
  • Nettles, DL; Haider, MA; Chilkoti, A; Setton, LA, Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds., Tissue Engineering Part A: Tissue Engineering, vol 16 no. 1 (2010), pp. 11-20 [10.1089/ten.tea.2009.0134] [abs].
  • MacEwan, SR; Chilkoti, A, Elastin-like polypeptides: biomedical applications of tunable biopolymers., Biopolymers, vol 94 no. 1 (2010), pp. 60-77 [10.1002/bip.21327] [abs].
  • MacKay, JA; Chen, M; McDaniel, JR; Liu, W; Simnick, AJ; Chilkoti, A, Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection., Nature Materials, vol 8 no. 12 (2009), pp. 993-999 [10.1038/nmat2569] [abs].
  • Cho, Y; Sagle, LB; Iimura, S; Zhang, Y; Kherb, J; Chilkoti, A; Scholtz, JM; Cremer, PS, Hydrogen bonding of beta-turn structure is stabilized in D(2)O., Journal of the American Chemical Society, vol 131 no. 42 (2009), pp. 15188-15193 [10.1021/ja9040785] [abs].
  • Gao, W; Liu, W; Mackay, JA; Zalutsky, MR; Toone, EJ; Chilkoti, A, In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics., Proceedings of the National Academy of Sciences of USA, vol 106 no. 36 (2009), pp. 15231-15236 [10.1073/pnas.0904378106] [abs].
  • Nettles, DL; Chilkoti, A; Setton, LA, Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds., Tissue Engineering Part A: Tissue Engineering, vol 15 no. 8 (2009), pp. 2113-2121 [10.1089/ten.tea.2008.0448] [abs].
  • Christensen, T; Amiram, M; Dagher, S; Trabbic-Carlson, K; Shamji, MF; Setton, LA; Chilkoti, A, Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins., Protein Science, vol 18 no. 7 (2009), pp. 1377-1387 [10.1002/pro.157] [abs].
  • Hucknall, A; Simnick, AJ; Hill, RT; Chilkoti, A; Garcia, A; Johannes, MS; Clark, RL; Zauscher, S; Ratner, BD, Versatile synthesis and micropatterning of nonfouling polymer brushes on the wafer scale., Biointerphases: an open access journal for the biomaterials interface community, vol 4 no. 2 (2009), pp. FA50-FA57 [10.1116/1.3151968] [abs].
  • Zauscher, S; Chilkoti, A, Biological applications of polymer brushes. Preface., Biointerphases: an open access journal for the biomaterials interface community, vol 4 no. 2 (2009), pp. FA1-FA2 [10.1116/1.3149787] [abs].
  • Nusz, GJ; Curry, AC; Marinakos, SM; Wax, A; Chilkoti, A, Rational selection of gold nanorod geometry for label-free plasmonic biosensors., ACS Nano, vol 3 no. 4 (2009), pp. 795-806 [10.1021/nn8006465] [abs].
  • Wu, Y; MacKay, JA; McDaniel, JR; Chilkoti, A; Clark, RL, Fabrication of elastin-like polypeptide nanoparticles for drug delivery by electrospraying., Biomacromolecules, vol 10 no. 1 (2009), pp. 19-24 [10.1021/bm801033f] [abs].
  • Chilkoti, A, Designing interfaces for optical biosensors (2009) [abs].
  • Crow, M; Marinakos, S; Chilkoti, A; Wax, A, Simultaneous molecular imaging of EGFR and HER2 using hyperspectral darkfield microscopy and immunotargeted nanoparticles, Proceedings of SPIE, vol 7192 (2009) [10.1117/12.808968] [abs].
  • Hucknall, A; Kim, DH; Rangarajan, S; Hill, RT; Reichert, WM; Chilkoti, A, Simple fabrication of antibody microarrays on nonfouling polymer brushes with femtomolar sensitivity for protein analytes in serum and blood, Advanced Materials, vol 21 no. 19 (2009), pp. 1968-1971 [10.1002/adma.200803125] [abs].
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  • Cho, Y; Zhang, Y; Christensen, T; Sagle, LB; Chilkoti, A; Cremer, PS, Effects of Hofmeister anions on the phase transition temperature of elastin-like polypeptides., The Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces and Biophysical, vol 112 no. 44 (2008), pp. 13765-13771 [10.1021/jp8062977] [abs].
  • Mackay, JA; Chilkoti, A, Temperature sensitive peptides: engineering hyperthermia-directed therapeutics., International Journal of Hyperthermia, vol 24 no. 6 (2008), pp. 483-495 [10.1080/02656730802149570] [abs].
  • Xu, F; Joon, HM; Trabbic-Carlson, K; Chilkoti, A; Knoll, W, Surface plasmon optical study of the interfacial phase transition of elastinlike polypeptide grafted on gold., Biointerphases: an open access journal for the biomaterials interface community, vol 3 no. 3 (2008), pp. 66-74 [10.1116/1.2965133] [abs].
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  • Shamji, MF; Chen, J; Friedman, AH; Richardson, WJ; Chilkoti, A; Setton, LA, Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist., Journal of Controlled Release, vol 129 no. 3 (2008), pp. 179-186 [10.1016/j.jconrel.2008.04.021] [abs].
  • Mock, JJ; Hill, RT; Degiron, A; Zauscher, S; Chilkoti, A; Smith, DR, Distance-dependent plasmon resonant coupling between a gold nanoparticle and gold film., Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol 8 no. 8 (2008), pp. 2245-2252 [10.1021/nl080872f] [abs].
  • Nettles, DL; Kitaoka, K; Hanson, NA; Flahiff, CM; Mata, BA; Hsu, EW; Chilkoti, A; Setton, LA, In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model., Tissue Engineering Part A: Tissue Engineering, vol 14 no. 7 (2008), pp. 1133-1140 [10.1089/tea.2007.0245] [abs].
  • Shamji, MF; Whitlatch, L; Friedman, AH; Richardson, WJ; Chilkoti, A; Setton, LA, An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration., Spine, vol 33 no. 7 (2008), pp. 748-754 [10.1097/BRS.0b013e3181695773] [abs].
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  • Dreher, MR; Simnick, AJ; Fischer, K; Smith, RJ; Patel, A; Schmidt, M; Chilkoti, A, Temperature triggered self-assembly of polypeptides into multivalent spherical micelles., Journal of the American Chemical Society, vol 130 no. 2 (2008), pp. 687-694 [10.1021/ja0764862] [abs].
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  • Chilkoti, A, Patterning materials with biomolecules, 8th World Biomaterials Congress 2008, vol 4 (2008), pp. 2249-2250 [abs].
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  • Shamji, MF; Betre, H; Kraus, VB; Chen, J; Chilkoti, A; Pichika, R; Masuda, K; Setton, LA, Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic., Arthritis and Rheumatism, vol 56 no. 11 (2007), pp. 3650-3661 [10.1002/art.22952] [abs].
  • Kim, DH; Smith, JT; Chilkoti, A; Reichert, WM, The effect of covalently immobilized rhIL-1ra-ELP fusion protein on the inflammatory profile of LPS-stimulated human monocytes., Biomaterials, vol 28 no. 23 (2007), pp. 3369-3377 [10.1016/j.biomaterials.2007.04.010] [abs].
  • Roberts, SK; Chilkoti, A; Setton, LA, Multifunctional thermally transitioning oligopeptides prepared by ring-opening metathesis polymerization., Biomacromolecules, vol 8 no. 8 (2007), pp. 2618-2621 [10.1021/bm0702713] [abs].
  • Marinakos, SM; Chen, S; Chilkoti, A, Plasmonic detection of a model analyte in serum by a gold nanorod sensor., Analytical Chemistry, vol 79 no. 14 (2007), pp. 5278-5283 [10.1021/ac0706527] [abs].
  • Dreher, MR; Chilkoti, A, Toward a systems engineering approach to cancer drug delivery., Journal of National Cancer Institute, vol 99 no. 13 (2007), pp. 983-985 [10.1093/jnci/djm042] [abs].
  • Valiaev, A; Lim, DW; Oas, TG; Chilkoti, A; Zauscher, S, Force-induced prolyl cis-trans isomerization in elastin-like polypeptides., Journal of the American Chemical Society, vol 129 no. 20 (2007), pp. 6491-6497 [10.1021/ja070147r] [abs].
  • Dreher, MR; Liu, W; Michelich, CR; Dewhirst, MW; Chilkoti, A, Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors., Cancer Research, vol 67 no. 9 (2007), pp. 4418-4424 [10.1158/0008-5472.CAN-06-4444] [abs].
  • Lim, DW; Nettles, DL; Setton, LA; Chilkoti, A, Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution., Biomacromolecules, vol 8 no. 5 (2007), pp. 1463-1470 [10.1021/bm061059m] [abs].
  • Lim, DW; Trabbic-Carlson, K; Mackay, JA; Chilkoti, A, Improved non-chromatographic purification of a recombinant protein by cationic elastin-like polypeptides., Biomacromolecules, vol 8 no. 5 (2007), pp. 1417-1424 [10.1021/bm060849t] [abs].
  • Curry, A; Nusz, G; Chilkoti, A; Wax, A, Analysis of total uncertainty in spectral peak measurements for plasmonic nanoparticle-based biosensors., Applied Optics, vol 46 no. 10 (2007), pp. 1931-1939 [abs].
  • Lee, WK; Chen, S; Chilkoti, A; Zauscher, S, Fabrication of gold nanowires by electric-field-induced scanning probe lithography and in situ chemical development., Small, vol 3 no. 2 (2007), pp. 249-254 [10.1002/smll.200600396] [abs].
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  • Christensen, T; Trabbic-Carlson, K; Liu, W; Chilkoti, A, Purification of recombinant proteins from Escherichia coli at low expression levels by inverse transition cycling., Analytical Biochemistry, vol 360 no. 1 (2007), pp. 166-168 [10.1016/j.ab.2006.09.020] [abs].
  • Lam, Y; Valiaev, A; Lim, DW; Chilkoti, A; Alam, SM; Zauscher, S, Single molecule nanomechanics of HIV-1 envelope glycoproteins and elastin-like polypeptides, Proceedings of the SEM Annual Conference and Exposition on Experimental and Applied Mechanics 2007, vol 1 (2007), pp. 624-625 [abs].
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  • Liu, W; Dreher, MR; Furgeson, DY; Peixoto, KV; Yuan, H; Zalutsky, MR; Chilkoti, A, Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice., Journal of Controlled Release, vol 116 no. 2 (2006), pp. 170-178 [10.1016/j.jconrel.2006.06.026] [abs].
  • Liu, WE; Dreher, MR; Furgeson, DY; Peixoto, KV; Yuan, H; Zalutsky, MR; Chilkoti, A, Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice, Journal of Controlled Release, vol 116 no. 2 (2006), pp. 170-178 [abs].
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  • Betre, H; Liu, W; Zalutsky, MR; Chilkoti, A; Kraus, VB; Setton, LA, A thermally responsive biopolymer for intra-articular drug delivery., Journal of Controlled Release, vol 115 no. 2 (2006), pp. 175-182 [10.1016/j.jconrel.2006.07.022] [abs].
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  • Zhang, Y; Trabbic-Carlson, K; Albertorio, F; Chilkoti, A; Cremer, PS, Aqueous two-phase system formation kinetics for elastin-like polypeptides of varying chain length., Biomacromolecules, vol 7 no. 7 (2006), pp. 2192-2199 [10.1021/bm060254y] [abs].
  • Chow, DC; Dreher, MR; Trabbic-Carlson, K; Chilkoti, A, Ultra-high expression of a thermally responsive recombinant fusion protein in E. coli., Biotechnology Progress, vol 22 no. 3 (2006), pp. 638-646 [10.1021/bp0503742] [abs].
  • Pyhtila, JW; Ma, H; Simnick, AJ; Chilkoti, A; Wax, A, Analysis of long range correlations due to coherent light scattering from in-vitro cell arrays using angle-resolved low coherence interferometry., Journal of Biomedical Optics, vol 11 no. 3 (2006) [10.1117/1.2209561] [abs].
  • Ma, H; Li, D; Sheng, X; Zhao, B; Chilkoti, A, Protein-resistant polymer coatings on silicon oxide by surface-initiated atom transfer radical polymerization., Langmuir: the ACS journal of surfaces and colloids, vol 22 no. 8 (2006), pp. 3751-3756 [10.1021/la052796r] [abs].
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  • Chilkoti, A, Bionanofabrication with polymers and enzymes, ACS National Meeting Book of Abstracts, vol 231 (2006) [abs].
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  • Dreher, MR; Liu, W; Michelich, CR; Dewhirst, MW; Yuan, F; Chilkoti, A, Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers., Journal of National Cancer Institute, vol 98 no. 5 (2006), pp. 335-344 [10.1093/jnci/djj070] [abs].
  • Hyun, J; Chen, J; Setton, LA; Chilkoti, A, Patterning cells in highly deformable microstructures: effect of plastic deformation of substrate on cellular phenotype and gene expression., Biomaterials, vol 27 no. 8 (2006), pp. 1444-1451 [10.1016/j.biomaterials.2005.08.018] [abs].
  • Ma, H; Textor, M; Clark, RL; Chilkoti, A, Monitoring kinetics of surface initiated atom transfer radical polymerization by quartz crystal microbalance with dissipation., Biointerphases: an open access journal for the biomaterials interface community, vol 1 no. 1 (2006) [10.1116/1.2190697] [abs].
  • Ong, SR; Trabbic-Carlson, KA; Nettles, DL; Lim, DW; Chilkoti, A; Setton, LA, Epitope tagging for tracking elastin-like polypeptides., Biomaterials, vol 27 no. 9 (2006), pp. 1930-1935 [10.1016/j.biomaterials.2005.10.018] [abs].
  • Furgeson, DY; Dreher, MR; Chilkoti, A, Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors., Journal of Controlled Release, vol 110 no. 2 (2006), pp. 362-369 [10.1016/j.jconrel.2005.10.006] [abs].
  • Betre, H; Ong, SR; Guilak, F; Chilkoti, A; Fermor, B; Setton, LA, Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide., Biomaterials, vol 27 no. 1 (2006), pp. 91-99 [10.1016/j.biomaterials.2005.05.071] [abs].
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  • Ma, H; Wells, M; Jr, TPB; Chilkoti, A, Surface-initiated atom transfer radical polymerization of oligo(ethylene glycol) methyl methacrylate from a mixed self-assembled monolayer on gold, Advanced Functional Materials, vol 16 no. 5 (2006), pp. 640-648 [10.1002/adfm.200500426] [abs].
  • McHale, MK; Setton, LA; Chilkoti, A, Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair., Tissue Engineering, vol 11 no. 11-12 (2005), pp. 1768-1779 [10.1089/ten.2005.11.1768] [abs].
  • Zhang, Z; Ma, H; Hausner, DB; Chilkoti, A; Beebe, TP, Pretreatment of amphiphilic comb polymer surfaces dramatically affects protein adsorption., Biomacromolecules, vol 6 no. 6 (2005), pp. 3388-3396 [10.1021/bm050446d] [abs].
  • Chow, DC; Lee, WK; Zauscher, S; Chilkoti, A, Enzymatic fabrication of DNA nanostructures: extension of a self-assembled oligonucleotide monolayer on gold arrays., Journal of the American Chemical Society, vol 127 no. 41 (2005), pp. 14122-14123 [10.1021/ja052491z] [abs].
  • Chilkoti, A, Passive and active surfaces to control protein and cell interactions, ACS National Meeting Book of Abstracts, vol 230 (2005), pp. U4150-U4151 [abs].
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  • Curry, A; Nusz, G; Chilkoti, A; Wax, A, Substrate effect on refractive index dependence of plasmon resonance for individual silver nanoparticles observed using darkfield microspectroscopy., Optics Express, vol 13 no. 7 (2005), pp. 2668-2677 [abs].
  • Chilkoti, A, Nano- to micro-scale structures of polymers that repel and attract proteins., ACS National Meeting Book of Abstracts, vol 229 (2005), pp. U1158-U1158 [abs].
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  • Haider, MA; Nettles, DL; Trabbic-Carlson, K; Chilkoti, A; Setton, LA, Predictive modeling of polypeptide hydrogel mechanical properties for cartilage repair using artificial neural networks, Proceedings of the 2005 Summer Bioengineering Conference, vol 2005 (2005), pp. 633-634 [abs].
  • Ma, H; Hyun, J; Zhang, Z; Jr, TPB; Chilkoti, A, Fabrication of biofunctionalized quasi-three-dimensional microstructures of a nonfouling comb polymer using soft lithography, Advanced Functional Materials, vol 15 no. 4 (2005), pp. 529-540 [10.1002/adfm.200400088] [abs].
  • Valiaev, A; Dong, WL; Chilkoti, A; Schmidler, S; Zauscher, S, Polypeptide-solvent interactions measured by single molecule force spectroscopy, Materials Research Society Symposium - Proceedings, vol 898 (2005), pp. 92-97 [abs].
  • Trabbic-Carlson, K; Liu, L; Kim, B; Chilkoti, A, Expression and purification of recombinant proteins from Escherichia coli: Comparison of an elastin-like polypeptide fusion with an oligohistidine fusion., Protein Science, vol 13 no. 12 (2004), pp. 3274-3284 [10.1110/ps.04931604] [abs].
  • Dreher, MR; Elas, M; Ichikawa, K; Barth, ED; Chilkoti, A; Rosen, GM; Halpern, HJ; Dewhirst, M, Nitroxide conjugate of a thermally responsive elastin-like polypeptide for noninvasive thermometry., Medical Physics, vol 31 no. 10 (2004), pp. 2755-2762 [abs].
  • Nath, N; Chilkoti, A, Label-free biosensing by surface plasmon resonance of nanoparticles on glass: optimization of nanoparticle size., Analytical Chemistry, vol 76 no. 18 (2004), pp. 5370-5378 [10.1021/ac049741z] [abs].
  • Nath, N; Chilkoti, A, Label free colorimetric biosensing using nanoparticles., Journal of Fluorescence, vol 14 no. 4 (2004), pp. 377-389 [abs].
  • Hyun, J; Lee, WK; Nath, N; Chilkoti, A; Zauscher, S, Capture and release of proteins on the nanoscale by stimuli-responsive elastin-like polypeptide "switches"., Journal of the American Chemical Society, vol 126 no. 23 (2004), pp. 7330-7335 [10.1021/ja049721e] [abs].
  • Meyer, DE; Chilkoti, A, Quantification of the effects of chain length and concentration on the thermal behavior of elastin-like polypeptides., Biomacromolecules, vol 5 no. 3 (2004), pp. 846-851 [10.1021/bm034215n] [abs].
  • Hyun, J; Kim, J; Craig, SL; Chilkoti, A, Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold., Journal of the American Chemical Society, vol 126 no. 15 (2004), pp. 4770-4771 [10.1021/ja049956q] [abs].
  • Piervincenzi, RT; Chilkoti, A, Effect of genetic circular permutation near the active site on the activity and stability of an enzyme inhibitor., New Biotechnology, vol 21 no. 1 (2004), pp. 33-42 [abs].
  • Trabbic-Carlson, K; Meyer, DE; Liu, L; Piervincenzi, R; Nath, N; LaBean, T; Chilkoti, A, Effect of protein fusion on the transition temperature of an environmentally responsive elastin-like polypeptide: a role for surface hydrophobicity?, Protein Engineering Design and Selection, vol 17 no. 1 (2004), pp. 57-66 [10.1093/protein/gzh006] [abs].
  • Ma, H; Hyun, J; Stiller, P; Chilkoti, A, "Non-Fouling" Oligo(ethylene glycol)-Functionalized Polymer Brushes Synthesized by Surface-Initiated Atom Transfer Radical Polymerization, Advanced Materials, vol 16 no. 4 (2004), pp. 338-341 [abs].
  • Nath, N; Hyun, J; Ma, H; Chilkoti, A, Surface engineering strategies for control of protein and cell interactions, Surface Science, vol 570 no. 1-2 (2004), pp. 98-110 [10.1016/j.susc.2004.06.182] [abs].
  • Wong, JY; Plant, AL; Schmidt, CE; Shea, L; Coury, AJ; Chen, CS; Barron, AE; Klok, HA; Deming, TJ; Saltzman, WM; Chilkoti, A; Luo, D; Uhrich, K, Materials Research Society Symposium Proceedings: Preface, Materials Research Society Symposium - Proceedings, vol EXS no. 1 (2004) [abs].
  • Dreher, MR; Raucher, D; Balu, N; Michael Colvin, O; Ludeman, SM; Chilkoti, A, Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy., Journal of Controlled Release, vol 91 no. 1-2 (2003), pp. 31-43 [abs].
  • Trabbic-Carlson, K; Setton, LA; Chilkoti, A, Swelling and mechanical behaviors of chemically cross-linked hydrogels of elastin-like polypeptides., Biomacromolecules, vol 4 no. 3 (2003), pp. 572-580 [10.1021/bm025671z] [abs].
  • Nath, N; Chilkoti, A, Fabrication of a reversible protein array directly from cell lysate using a stimuli-responsive polypeptide., Analytical Chemistry, vol 75 no. 4 (2003), pp. 709-715 [abs].
  • Chan, BP; Chilkoti, A; Reichert, WM; Truskey, GA, Effect of streptavidin affinity mutants on the integrin-independent adhesion of biotinylated endothelial cells., Biomaterials, vol 24 no. 4 (2003), pp. 559-570 [abs].
  • Blomfield, CJ; Roberts, AJ; Hutton, SJ; Ma, H; Hyun, J; Chilkoti, A, X-ray photoelectron spectroscopy as a tool for bio-surface analysis, European Cells and Materials, vol 6 no. SUPPL. 1 (2003) [abs].
  • Frey, W; Meyer, DE; Chilkoti, A, Dynamic addressing of a surface pattern by a stimuli-responsive fusion protein, Advanced Materials, vol 15 no. 3 (2003), pp. 248-251 [10.1002/adma.200390058] [abs].
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  • Hyun, J; Ma, H; Zhang, Z; Jr, TPB; Chilkoti, A, Universal route to cell micropatterning using an amphiphilic comb polymer, Advanced Materials, vol 15 no. 7-8 (2003), pp. 576-579 [abs].
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  • Chilkoti, A; Dreher, MR; Meyer, DE, Design of thermally responsive, recombinant polypeptide carriers for targeted drug delivery., Advanced Drug Delivery Reviews, vol 54 no. 8 (2002), pp. 1093-1111 [abs].
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  • Betre, H; Setton, LA; Meyer, DE; Chilkoti, A, Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair., Biomacromolecules, vol 3 no. 5 (2002), pp. 910-916 [abs].
  • Meyer, DE; Chilkoti, A, Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system., Biomacromolecules, vol 3 no. 2 (2002), pp. 357-367 [abs].
  • Nath, N; Chilkoti, A, A colorimetric gold nanoparticle sensor to interrogate biomolecular interactions in real time on a surface., Analytical Chemistry, vol 74 no. 3 (2002), pp. 504-509 [abs].
  • Betre, H; Chilkoti, A; Setton, LA, A two-step chondrocyte recovery system based on thermally sensitive elastin-like polypeptide scaffolds for cartilage tissue engineering, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol 1 (2002), pp. 829-830 [abs].
  • Dreher, M; Raucher, D; Balu, N; Colvin, M; Ludeman, S; Chilkoti, A, Elastin-like polypeptide-doxorubicin conjugates for cancer therapy, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol 1 (2002), pp. 524-525 [abs].
  • Hyun, J; Ahn, SJ; Lee, WK; Chilkoti, A; Zauscher, S, Molecular recognition-mediated fabrication of protein nanostructures by dip-pen lithography, Nano Lett. (USA), vol 2 no. 11 (2002), pp. 1203-1207 [10.1021/n10257364] [abs].
  • Hyun, J; Ahn, SJ; Lee, WK; Chilkoti, A; Zauscher, S, Molecular Recognition-Mediated Fabrication of Protein Nanostructures by Dip-Pen Lithography, Nano Letters, vol 2 no. 11 (2002), pp. 1203-1207 [10.1021/nl0257364] [abs].
  • Hyun, J; Ma, H; Banerjee, P; Cole, J; Gonsalves, K; Chilkoti, A, Micropatterns of a cell-adhesive peptide on an amphiphilic comb polymer film, Langmuir, vol 18 no. 8 (2002), pp. 2975-2979 [10.1021/la015712x] [abs].
  • Nath, N; Chilkoti, A, Creating "smart" surfaces using stimuli responsive polymers, Advanced Materials, vol 14 no. 17 (2002), pp. 1243-1247 [10.1002/1521-4095(20020903)14:173.0.CO;2-M] [abs].
  • Nath, N; Chilkoti, A, An immobilized gold nanoparticle sensor for label free optical detection of biomolecular interactions, Proceedings of SPIE - The International Society for Optical Engineering, vol 4626 (2002), pp. 441-448 [10.1117/12.472110] [abs].
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  • Nath, N; Chilkoti, A, A colorimetric gold nanoparticle biosensor: Effect of particle size on sensitivity, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol 1 (2002), pp. 574-575 [abs].
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  • Raucher, D; Chilkoti, A, Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition., Cancer Research, vol 61 no. 19 (2001), pp. 7163-7170 [abs].
  • Nath, N; Chilkoti, A, Interfacial phase transition of an environmentally responsive elastin biopolymer adsorbed on functionalized gold nanoparticles studied by colloidal surface plasmon resonance., Journal of the American Chemical Society, vol 123 no. 34 (2001), pp. 8197-8202 [abs].
  • Hyun, J; Chilkoti, A, Micropatterning biological molecules on a polymer surface using elastomeric microwells., Journal of the American Chemical Society, vol 123 no. 28 (2001), pp. 6943-6944 [abs].
  • Meyer, DE; Shin, BC; Kong, GA; Dewhirst, MW; Chilkoti, A, Drug targeting using thermally responsive polymers and local hyperthermia., Journal of Controlled Release, vol 74 no. 1-3 (2001), pp. 213-224 [abs].
  • Meyer, DE; Trabbic-Carlson, K; Chilkoti, A, Protein purification by fusion with an environmentally responsive elastin-like polypeptide: effect of polypeptide length on the purification of thioredoxin., Biotechnology Progress, vol 17 no. 4 (2001), pp. 720-728 [10.1021/bp010049o] [abs].
  • Meyer, DE; Kong, GA; Dewhirst, MW; Zalutsky, MR; Chilkoti, A, Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia., Cancer Research, vol 61 no. 4 (2001), pp. 1548-1554 [abs].
  • Belu, AM; Yang, Z; Aslami, R; Chilkoti, A, Enhanced TOF-SIMS imaging of a micropatterned protein by stable isotope protein labeling., Analytical Chemistry, vol 73 no. 2 (2001), pp. 143-150 [abs].
  • Hyun, J; Chilkoti, A, Surface-initiated free radical polymerization of polystyrene micropatterns on a self-assembled monolayer on gold, Macromolecules, vol 34 no. 16 (2001), pp. 5644-5652 [10.1021/ma002125u] [abs].
  • Hyun, J; Zhu, Y; Liebmann-Vinson, A; Jr, TPB; Chilkoti, A, Microstamping on an activated polymer surface: Patterning biotin and streptavidin onto common polymeric biomaterials, Langmuir: the ACS journal of surfaces and colloids, vol 17 no. 20 (2001), pp. 6358-6367 [10.1021/la010695x] [abs].
  • Stayton, PS; Hoffman, AS; Murthy, N; Lackey, C; Cheung, C; Tan, P; Klumb, LA; Chilkoti, A; Wilbur, FS; Press, OW, Molecular engineering of proteins and polymers for targeting and intracellular delivery of therapeutics., Journal of Controlled Release, vol 65 no. 1-2 (2000), pp. 203-220 [abs].
  • Chilkoti, A; Hyun, J; Belu, A; Yang, Z, Microstamping of biological ligands on activated polymer surfaces, Annals of Biomedical Engineering, vol 28 no. SUPPL 1 (2000) [abs].
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  • Frey, W; Chilkoti, A, Ultraflat nanosphere lithography: functionalized nanostructures for biomedical applications, Annals of Biomedical Engineering, vol 28 no. SUPPL 1 (2000) [abs].
  • Frey, W; Chilkoti, A, Ultraflat nanosphere lithography: functionalized nanostructures for biomedical applications, Annals of Biomedical Engineering, vol 28 no. SUPPL. 1 (2000), pp. S-94 [abs].
  • Frey, W; Woods, CK; Chilkoti, A, Ultraflat nanosphere lithography: a new method to fabricate flat nanostructures, Adv. Mater. (Germany), vol 12 no. 20 (2000), pp. 1515-1519 [10.1002/1521-4095(200010)12:203.0.CO;2-J] [abs].
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  • Meyer, D; Chilkoti, A, Engineered fusion protein of an elastin-like polypeptide and autofluorescent proteins: a genetically encodable nanobiosensor, Annals of Biomedical Engineering, vol 28 no. SUPPL 1 (2000) [abs].
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  • Meyer, DE; Kong, GA; Dewhirst, MW; Foulon, C; Zalutsky, MR; Chilkoti, A, Genetically engineered polypeptide carrier for thermal targeting of anticancer therapeutics, American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, vol 41 no. 1 (2000), pp. 1020-1021 [abs].
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  • Yang, Z; Frey, W; Oliver, T; Chilkoti, A, Light-activated affinity micropatterning of proteins on self-assembled monolayers on gold, Langmuir (USA), vol 16 no. 4 (2000), pp. 1751-1758 [10.1021/la998079] [abs].
  • Yang, Z; Frey, W; Oliver, T; Chilkoti, A, Light-activated affinity micropatterning of proteins on self-assembled monolayers on gold, Langmuir, vol 16 no. 4 (2000), pp. 1751-1758 [10.1021/la9908079] [abs].
  • Freitag, S; Le Trong, I; Klumb, LA; Chu, V; Chilkoti, A; Stayton, PS; Stenkamp, RE, X-ray crystallographic studies of streptavidin mutants binding to biotin., New Biotechnology, vol 16 no. 1-4 (1999), pp. 13-19 [abs].
  • Stayton, PS; Freitag, S; Klumb, LA; Chilkoti, A; Chu, V; Penzotti, JE; To, R; Hyre, D; Le Trong, I; Lybrand, TP; Stenkamp, RE, Streptavidin-biotin binding energetics., New Biotechnology, vol 16 no. 1-4 (1999), pp. 39-44 [abs].
  • Wong, J; Chilkoti, A; Moy, VT, Direct force measurements of the streptavidin-biotin interaction., New Biotechnology, vol 16 no. 1-4 (1999), pp. 45-55 [abs].
  • Meyer, DE; Chilkoti, A, Purification of recombinant proteins by fusion with thermally-responsive polypeptides., Nature Biotechnology, vol 17 no. 11 (1999), pp. 1112-1115 [10.1038/15100] [abs].
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  • Freitag, S; Le Trong, I; Chilkoti, A; Klumb, LA; Stayton, PS; Stenkamp, RE, Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex., Journal of Molecular Biology, vol 279 no. 1 (1998), pp. 211-221 [10.1006/jmbi.1998.1735] [abs].
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  • Shimoboji, T; Stayton, PS; Long, C; Chilkoti, A; Chen, G; Harris, JM; Hoffman, AS, Site-specific conjugation of a temperature-sensitive polymer to a genetically-engineered protein, Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, vol 1 (1996) [abs].
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  • Chilkoti, A; Boland, T; Ratner, BD; Stayton, PS, The relationship between ligand-binding thermodynamics and protein-ligand interaction forces measured by atomic force microscopy., Biophysical Journal, vol 69 no. 5 (1995), pp. 2125-2130 [10.1016/S0006-3495(95)80083-4] [abs].
  • Chilkoti, A; Schwartz, BL; Smith, RD; Long, CJ; Stayton, PS, Engineered chimeric streptavidin tetramers as novel tools for bioseparations and drug delivery., Biotechnology, vol 13 no. 11 (1995), pp. 1198-1204 [abs].
  • Chilkoti, A; Schmierer, AE; Pérez-Luna, VH; Ratner, BD, Investigating the relationship between surface chemistry and endothelial cell growth: partial least-squares regression of the static secondary ion mass spectra of oxygen-containing plasma-deposited films., Analytical Chemistry, vol 67 no. 17 (1995), pp. 2883-2891 [abs].
  • Chilkoti, A; Tan, PH; Stayton, PS, Site-directed mutagenesis studies of the high-affinity streptavidin-biotin complex: contributions of tryptophan residues 79, 108, and 120., Proceedings of the National Academy of Sciences of USA, vol 92 no. 5 (1995), pp. 1754-1758 [abs].
  • Chilkoti, A; Stayton, PS, Molecular origins of the slow streptavidin-biotin dissociation kinetics, Journal of the American Chemical Society, vol 117 no. 43 (1995), pp. 10622-10628 [abs].
  • Schwartz, BL; Bruce, JE; Anderson, GA; Hofstadler, SA; Rockwood, AL; Smith, RD; Chilkoti, A; Stayton, PS, Dissociation of tetrameric ions of noncovalent streptavidin complexes formed by electrospray ionization, Journal of the American Society for Mass Spectrometry, vol 6 no. 6 (1995), pp. 459-465 [10.1016/1044-0305(95)00191-F] [abs].
  • Schwartz, BL; Gale, DC; Smith, RD; Chilkoti, A; Stayton, PS, Investigation of non-covalent ligand binding to the intact streptavidin tetramer by electrospray ionization mass spectrometry, Journal of Mass Spectrometry, vol 30 no. 8 (1995), pp. 1095-1102 [10.1002/jms.1190300806] [abs].
  • Chilkoti, A; Chen, G; Stayton, PS; Hoffman, AS, Site-specific conjugation of a temperature-sensitive polymer to a genetically-engineered protein., Bioconjugate Chemistry, vol 5 no. 6 (1994), pp. 504-507 [abs].
  • Chilkoti, A; Ratner, BD; Briggs, D, Static secondary ion mass spectrometric investigation of the surface chemistry of organic plasma-deposited films created from oxygen-containing precursors. 3. Multivariate statistical modeling., Analytical Chemistry, vol 65 no. 13 (1993), pp. 1736-1745 [abs].
  • Chilkoti, A; Lopez, GP; Ratner, BD, Analysis of polymer surfaces by SIMS. 16. investigation of surface cross-linking in polymer gels of 2-hydroxyethyl methacrylate, Macromolecules, vol 26 no. 18 (1993), pp. 4825-4832 [abs].
  • Chilkoti, A; Ratner, BD, X-ray photoelectron spectroscopy of iodine-doped nonconjugated polymers, Chemistry of Materials, vol 5 no. 6 (1993), pp. 786-792 [abs].
  • Ratner, BD; Tyler, BJ; Chilkoti, A, Analysis of biomedical polymer surfaces: polyurethanes and plasma-deposited thin films., Clinical Materials, vol 13 no. 1-4 (1993), pp. 71-84 [abs].
  • Stayton, PS; Chilkoti, A; Long, CJ; Pettit, DK; Tan, PHS; Chen, G; Hoffman, AS, Engineered proteins for biomaterials, Materials Research Society Symposium Proceedings, vol 292 (1993), pp. 77-82 [abs].
  • Chilkoti, A; Ratner, BD; Briggs, D; Reich, F, Static secondary ion mass spectrometry of organic plasma-deposited films created from stable isotope-labeled precursors. II. Mixtures of acetone and oxygen, Journal of Polymer Science Part A: Polymer Chemistry, vol 30 no. 7 (1992), pp. 1261-1278 [10.1002/pola.1992.080300704] [abs].
  • Chilkoti, A; Ratner, BD; Briggs, D, Analysis of polymer surfaces by SIMS: part 15. oxygen-functualized aliphatic homopolymers, Surface and Interface Analysis, vol 18 no. 8 (1992), pp. 604-618 [abs].
  • Lopez, GP; Chilkoti, A; Briggs, D; Ratner, BD, Substrate temperature effects on film chemistry in plasma deposition of organics. III. Analysis by static secondary ion mass spectrometry, Journal of Polymer Science, Part A: Polymer Chemistry, vol 30 no. 11 (1992), pp. 2427-2441 [10.1002/pola.1992.080301117] [abs].
  • Ratner, BD; Chilkoti, A; Castner, DG, Contemporary methods for characterizing complex biomaterial surfaces, Clinical Materials, vol 11 no. 1-4 (1992), pp. 25-36 [abs].
  • Chilkoti, A; Ratner, BD; Briggs, D, Static secondary-ion mass spectrometric investigation of the surface structure of organic plasma-deposited films prepared from stable-isotope-labeled precursors. 1. Carbonyl precursors., Analytical Chemistry, vol 63 no. 15 (1991), pp. 1612-1620 [abs].
  • CHILKOTI, A; CASTNER, D; RATNER, B, STATIC SECONDARY ION MASS-SPECTROMETRY AND X-RAY PHOTOELECTRON-SPECTROSCOPY OF DEUTERIUM-SUBSTITUTED AND METHYL-SUBSTITUTED POLYSTYRENE, Applied Spectroscopy, vol 45 no. 2 (1991), pp. 209-217 [10.1366/0003702914337588] [abs].
  • Chilkoti, A; Ratner, BD; Briggs, D, Plasma-deposited polymeric films prepared from carbonyl-containing volatile precursors: XPS chemical derivatization and static SIMS surface characterization, Chemistry of Materials, vol 3 no. 1 (1991), pp. 51-61 [abs].
  • Chilkoti, A; Ratner, BD; Briggs, D, Structural elucidation of oxygen-containing plasma deposited films by static secondary ion mass spectrometry, Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, vol 14 (1991) [abs].
  • Chilkoti, A; Ratner, BD, X-ray photoelectron spectroscopic investigation of the selectivity of hydroxyl derivatization reactions, Surface and Interface Analysis, vol 17 no. 8 (1991), pp. 567-574 [abs].
  • Ertel, SI; Chilkoti, A; Horbett, TA; Ratner, BD, Endothelial cell growth on oxygen-containing films deposited by radio-frequency plasmas: the role of surface carbonyl groups., Journal of Biomaterials Science: Polymer Edition, vol 3 no. 2 (1991), pp. 163-183 [abs].
  • Leggett, GJ; Chilkoti, A; Castner, DG; Ratner, BD; Vickerman, JC, Direct emission of molecular fragments during the sputtering of poly(4-hydroxystyrene) and determination of ion structures using tandem secondary ion mass spectrometry, International Journal of Mass Spectrometry and Ion Processes, vol 108 no. 1 (1991), pp. 29-39 [abs].
  • Chilkoti, A; Ratner, BD; Briggs, D, Static SIMS investigation of the surface structure of plasma deposited films prepared from stable isotope-labeled carbonyl precursors, Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, vol 62 (1990), pp. 135-139 [abs].
  • Chilkoti, A; Ratner, BD, Effect of monomer type on the surface chemistry of rf-plasma deposited surfaces prepared for cell culture, Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, vol 59 (1988), pp. 258-262 [abs].